The absorption of aliphatic carbamates by everted gut sacs of rat
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منابع مشابه
Enhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS
Etoposide, a widely used anticancer drug, exhibits low and variable oral bioavailability mainly because of being substrate for the efflux transporter, P-glycoprotein (P-gp). Therefore, the present study was aimed to investigate the effect of D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) and PEG 400 as P-gp inhibitors on the intestinal absorption of etoposide. Everted sacs of rat smal...
متن کاملEnhanced Permeability of Etoposide across Everted Sacs of Rat Small Intestine by Vitamin E-TPGS
Etoposide, a widely used anticancer drug, exhibits low and variable oral bioavailability mainly because of being substrate for the efflux transporter, P-glycoprotein (P-gp). Therefore, the present study was aimed to investigate the effect of D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) and PEG 400 as P-gp inhibitors on the intestinal absorption of etoposide. Everted sacs of rat smal...
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To investigate the absorption and the inhibition of glucose by the aqueous seed extracts of Trigonella foenum gracum. The small intestine of all animals were removed, washed with 0.9% (w/v) normal saline and intestinal segments were everted the empty sac was filled with 0.5 ml of the KHB buffer and placed in a stoppered conical flask with 5 ml of the buffer with varying concentration of glucose...
متن کاملPhenol red inhibits uptake of phosphate by the everted gut sacs of mice.
Uptake of phosphate by the everted intestinal sacs of mice was measured at various concentrations of this anion in the incubation medium. Phenol red when added to the serosal side was able to inhibit the uptake of phosphate significantly, while uptake of glucose or proline was unaffected. When para amino hippuric acid was present along with phenol red in the serosal compartment, the inhibition ...
متن کاملAutoradiographic Study of Sugar and Amino Acid Absorption by Everted Sacs of Hamster Intestine
Autoradiographs were prepared from frozen sections of everted sacs of hamster jejunum which had been incubated in vitro with C(14)- or H(3)-labeled sugars and amino acids. When such tissue was incubated in 1 mM solutions of L-valine or L-methionine, columnar absorptive cells at tips of villi accumulated these amino acids to concentrations ranging from 5 to 50 millimoles per liter of cells. Quan...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1972
ISSN: 0306-3283
DOI: 10.1042/bj1280141pb